Σύνοψη

References:

• Zhu, Yanlin; Wang, Fen; Li, Quan; Zhu, Mingshe; Du, Alicia; Tang, Wei; Chen, Weighing (2014). "Amlodipine Metabolism in Human Liver Microsomes and Roles of CYP3A4/5 in the Dihydropyridine Dehydrogenation". Drug Metabolism and Disposition 42 (2): 245-249. DOI:10.1124/dmd.113.055400. PMID 24301608. ISSN 0090-9556.

Made using the chemfig package in LaTex.

\documentclass[10pt]{article}
\usepackage{chemfig}

\setdoublesep{0.091 cm}             % Bond Spacing
\setatomsep{14.4 pt}                % Bond length
\setcrambond{2 pt}{1 pt}{2.5 pt}    % {Bold width}{1pt}{Hash spacing}
\setbondoffset{1.6 pt}              % Margin Width
\setbondstyle{line width=0.6 pt}    % Line width 
\renewcommand*\printatom[1]{\normalsize \ensuremath{\mathsf{#1}}} 
    
\begin{document}
\schemestart
\chemfig{
    -[:90]O -[:30] (=[:90,0.75]O) -[:-30]
    *6(
    = (-[:210])
    -\chembelow{N}{H}
    - (-[:-30] -[:30]O -[:-30] -[:30] -[:-30]NH_2 )
    = ( -[:30](=[:90,0.75]O) -[:-30]O -[:30] )
    - ( -[:90,1.5] *6( - (-[,.75]Cl)
                   =
                   -
                   =
                   -
                   =
                   ) )
    - )
}
\arrow{->}
\hspace{0.7 cm}
\chemfig{
    -[:90]O -[:30] (=[:90,0.75]O) -[:-30]
    *6(
    =[,,,,magenta] (-[:210])
    -[,,,,magenta]\color{magenta}{N}
    =[,,,,magenta] (-[:-30] -[:30]\color{magenta}{OH} )
    -[,,,,magenta] ( -[:30](=[:90,0.75]O) -[:-30]\color{magenta}{OH} )
    =[,,,,magenta] ( -[:90,1.5] *6( - (-[,.75]Cl)
                   =
                   -
                   =
                   -
                   =
                   ) )
    -[,,,,magenta] )
}
\schemestop
\end{document}

Αδειοδότηση

This image of a simple structural formula is ineligible for copyright and therefore in the public domain, because it consists entirely of information that is common property and contains no original authorship.